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What are Barr bodies?
A Barr body (named after discoverer Murray Barr) is the inactive X chromosome in a female somatic cell, rendered inactive in a process called lyonization, in those species in which sex is determined by the presence of the Y (including humans) or W chromosome rather than the diploidy of the X or Z. The Lyon hypothesis states that in cells with ...
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X-inactivation Explained
If females have two X chromosomes and males have only one, why doesn’t that create a biological imbalance? In 1961, British geneticist Mary Lyon proposed a simple theory of X-chromosome inactivation in females. Lyon explained that, During early embryonic development, each cell in a female embryo makes a random choice. It switches off one X chromosome, either the maternal X or the paternal X. This choice remains permanent, and all daughter cells inherit the same inactivated X chromosome throughou
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If females have two X chromosomes and males have only one, why doesn’t that create a biological imbalance? In 1961, British geneticist Mary Lyon proposed a simple theory of X-chromosome inactivation in females. Lyon explained that, During early embryonic development, each cell in a female embryo makes a random choice. It switches off one X chromosome, either the maternal X or the paternal X. This choice remains permanent, and all daughter cells inherit the same inactivated X chromosome throughou
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