Asma Kamal on Instagram: "That’s a wrap on lymphomas. -Investigation of choice in both cases is excision lymph node biopsy. -Immunophenotypic markers? • HL is usually CD30 and CD15 and the non classical type shows strong CD45 positivity. • NHL shows pan B cell markers (CD 20, CD19) , rare cases T cell markers (CD3,4,8) ⁠ -FISH is an additional investigation done in nonhodgkins lymphoma. What is it? You basically “FISH” for choromosomal translocations using a fluorescent probe which is why it’s c
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med's go on Instagram: "The correct answer is C) CD34. CD34 is currently the most widely accepted and most specific surface marker for identifying human hematopoietic stem and progenitor cells (HSPCs). While CD45 is expressed on all hematopoietic cells (both stem cells and mature blood cells), CD3 is a T-cell marker and CD19 is a B-cell marker. CD34, on the other hand, is strongly expressed on early hematopoietic stem cells and progenitor cells, but its expression is lost as cells mature into mo
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