A novel collaboration may establish a framework to help researchers overcome regulatory barriers they often face when ...

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

Clinical psychology has long recognized that psychological distress and therapeutic change involve more than cognitive processes alone. Emotion regulation, ...

SAN DIEGO, CA—Does the use of a primary composite endpoint help or harm when it comes to interpreting modern-day clinical trials? Do softer clinical endpoints, such as recurrent angina, restenosis, or ...

Parents' Experiences With and Preferences for Receiving Information About Tumor Genomic Sequencing: Findings From a Qualitative Study and Implications for Practice For a 2-year overall survival end ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. A test-negative observational study design may be best ...

High-quality evidence is what we use to guide medical practice. The standard approach to generating this evidence — a series of clinical trials, each investigating one or two interventions in a single ...