Cancer-killing T cells have been programmed to have two levels of specificity. First, the T cells have been equipped with a receptor sensitive to a protein that is found only in central nervous system ...

Scientists at Rutgers University–Newark have developed a first-of-its-kind RNA-based nanotechnology that assembles itself ...

Cells have the remarkable ability to initiate their own death through a mechanism called programmed cell death, also known as apoptosis. Apoptosis contains sophisticated signalling pathways and ...

A team of researchers at the University of Cologne’s Center for Biochemistry, together with the Bambino Gesù Pediatric Hospital in Rome, Italy, have discovered a fundamental biological mechanism that ...

New basic science insights into programmed cell death could offer relief for inflammatory bowel disease. Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, ...

This paper explores the potential of mitochondrial-associated programmed-cell-death (mtPCD) patterns as biomarkers for predicting the prognosis of non-small-cell lung cancer (NSCLC). NSCLC is the most ...

Programmed cell death (PCD) stands at the forefront of innovation in experimental pharmacology and drug discovery, providing fundamental insights into ...

A new predictive framework reprograms T cells to sustain immune memory while preserving their ability to fight cancer and infections.

This finding, he suggests, helps link the study of cell death in the worm and oncogenesis in people. "There were a number of papers that had suggested a relationship between cell death and oncogenesis ...

The federal government is looking for researchers who can, in 5 years, develop stem cell treatments to repair brain damage caused by stroke, neurodegeneration, and trauma. The Functional Repair of ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...