Scientists uncover a new “recipe” that shows how exhausted T cells can be reprogrammed to regain their ability to attack tumors.

Scientists discovered key genetic factors that determine whether a T cell acts as a powerful disease fighter or enters an ineffective, exhausted state. Turning off two transcription factors allowed ...

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine ...

Powerful white blood cells referred to as CD8 killer T cells enable the body to control infections and fight cancer. But when they become exhausted, they can become dysfunctional and ineffective.

"Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?" There are instances where killer T cells—which are meant to precisely remove virus-infected ...

In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite ...

Researchers at UC San Francisco have uncovered a new clue to how Epstein-Barr virus (EBV) could contribute to multiple sclerosis (MS), a chronic autoimmune disease that affects nearly one million ...

“Why do immune cells that are supposed to eliminate viruses suddenly turn against our own body?” There are instances where killer T cells—which are meant to precisely remove virus-infected ...

Invariant natural killer T (iNKT) cells represent a unique lymphocyte subset that bridges innate and adaptive immunity. Their development originates in the thymus from double‐positive precursor cells, ...

Researchers expanded millions of cancer-targeting NK cells from a single donor, improving manufacturing for future therapies.