In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Explore how advances in accuracy, throughput and cost are making long-read sequencing more accessible at scale.

Scheme showing the structure of cytosine, 5-methylcytosine, and 5-hydroxymethylcytosine. Adding a methyl group to the DNA base cytosine represses gene expression in mammalian cells. To remove the ...

Oxford Nanopore long-read sequencing helps researchers derive insights from difficult-to-read genomic sections and detect large structural variants. However, the technique uses high molecular weight ...