The generation of durable CD8+ T cell memory following infection or vaccination is essential for protection against future encounters with the same or related pathogens. This process has traditionally ...

Flow cytometry, invented in the 1950s, uses antibodies linked to fluorescent probes to detect cell surface and intracellular proteins. Although able to achieve single-cell sensitivity, the method is ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

Over the past five years, the FCSC has invested $3.5 million in replacing or updating its instruments, expanding capacity, and developing new services such as multiplex immunofluorescence, Hanumanthu ...

Guo, Liu, and their colleagues studied the intercellular flow in a variety of biological tissues, including cells derived from pancreatic tissue. They carried out experiments in which they first ...

Flow cytometry offers practical advantages for real-time monitoring of CAR T cell expansion, persistence, and toxicity risk in aggressive large B-cell lymphoma patients. Early CAR T cell expansion is ...

As for many antibody-based experiments, labeling challenges related to brightness, signal stability, target detection, and background noise are common roadblocks in flow cytometry. Scientists can ...

Scientists are uncovering surprising ways in which cells resist programmed death, revealing mechanisms that could transform cancer treatment. New tools like multiparametric flow cytometry and metallic ...

Water makes up around 60 percent of the human body. More than half of this water sloshes around inside the cells that make up organs and tissues. Much of the remaining water flows in the nooks and ...