THE coumarin anticoagulants depress the synthesis of four clotting factors: prothrombin; proconvertin (factor VII); Stuart factor (factor X); and plasma thromboplastin component, or PTC (factor IX).
ACTIVE bleeding, the threat of bleeding or bleeding in the immediate past remains the only definite contraindication to the use of artificial-kidney hemodialysis. 1–3 Predialysis heparinization of the ...
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