Targeted CRISPR lipid nanoparticles eliminated 50% of tumors in mice with head and neck cancer. Researchers from Tel Aviv University (Israel), led by Razan Masarwy, have investigated utilizing CRISPR ...
Scientists design therapeutic approaches for cancer around mutations and variations that affect disease onset and progression. However, these determinants can differ across populations, and what ...
A compact Cas12f nuclease shows high editing efficiency in human cells, with structural insights enabling an engineered variant potentially suited for future AAV‑compatible delivery.
Gene therapy has experienced an increasing number of successful human clinical trials, leading to numerous FDA-approved therapies based on recombinant viruses for rare disease, cancer, and other ...
Super-enhancers (SEs) are large clusters of transcriptional regulatory elements that drive oncogene expression, maintain ...
NIH-funded UT team and colleagues from Metagenomi Thereapeutics discovered highly efficient enzyme could enable targeted gene editing within the human body.
The global cell therapy technologies market is set to grow from USD 4.41 billion in 2025 to USD 7.91 billion by 2030, ...
In a major step forward for cancer care, researchers at ChristianaCare's Gene Editing Institute have shown that disabling the NRF2 gene with CRISPR technology can reverse chemotherapy resistance in ...
“While recent single-cell multiomics studies and CRISPR screens in murine NK cells have expanded our understanding, actionable genomic targets in primary human NK cells have remained largely ...
On October 22, Nobel Prize–winning biochemist Dr. Jennifer Doudna dined with supporters of UCSB Arts & Lectures (A&L) and the Cancer Foundation of S.B. (CFSB). The intimate, al fresco dinner party at ...