A new study, led by researchers from the University of California, Irvine (UCI), uncovers the long-sought-after, three-dimensional structure of a toxin primarily responsible for devastating ...

A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...

Pfizer's preventative vaccine against Clostridium difficile has passed a phase 2 test and will start registration studies in the next few months, in hot pursuit of a rival candidate from Sanofi.

Cdiffense trial to evaluate vaccine against a leading cause of life-threatening, healthcare-associated infections worldwide SWIFTWATER, Pa., Aug. 5, 2013 /PRNewswire/ -- Sanofi Pasteur, the vaccines ...

The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a ...

A trio of researchers has identified the location of the genes that control production of toxins that harm people infected by Clostridium difficile bacteria. The gene locus, agr1, forms part of a ...

American researchers have discovered the process by which the cells in the gut fight off toxins produced by a hospital bug - Clostridium difficile. Writing in Nature Medicine, they showed how a ...