In a healthy body, mast cells (the “lookout” cells of the immune system) only release histamine when they detect a foreign invader, like pollen or venom. In CSU, these cells dump histamine into the ...

Angioedema without wheals (AE) is a distinct clinical condition characterized by self-limiting and localized edema that occurs without the presence of urticaria. This condition manifests as swelling ...

Hereditary angioedema (HAE) is a rare condition that causes fluid to build up throughout your body, triggering sudden and repeated serious swelling. This is the most common type and happens because of ...

AAEM statements are not to be construed as dictating an exclusive course of action nor are they intended to replace the medical judgment of healthcare professionals. The unique circumstances of ...

Medically reviewed by Casey Gallagher, MD CSU is a skin condition that causes hives and swelling lasting six weeks or more.The cause of the condition is often unknown, but in the majority of cases ...

Angioedema and anaphylaxis are two different conditions, but they share many of the same triggers and symptoms. Angioedema is swelling in the tissues underneath the skin. It’s marked by sudden changes ...

Hives (urticaria) are a common skin reaction that causes bumps, raised patches, or both. They are one way the body responds to an allergen or trigger. Reactions can be uncomfortable but aren’t ...

A person with hereditary angioedema (HAE) should seek emergency care during an HAE episode if they are having difficulty breathing or experiencing swelling of the tongue or throat, which could lead to ...

If you're being treated for hives, your physician will want to hear what you think about your treatment. Is it working? Are your symptoms improving, staying the same, or getting worse? You may be ...